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Multi Drug Resistance Assay

To assess activity of ABC transporters following drug treatment.
​
Features of the assay
  • Quan­titative evaluation of ABC transporters by fluorescence microscopy.​​

Untreated A498 cells
Cells were treated with a mix of inhibitors of ABC transporters. Nuclei were highlighted in blue and multi-drug resistance inhibition is highlighted in green. Left image: untreated cells. Center image: treated cells. The mean green fluorescence intensity in each cell, proportional to inhibition of ABC transporters, was quantified by digital imaging. 3500 cells were quantified for each condition and Mann-Whitney U test was performed to assess statistical differences. 

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ABOUT US
Kitos Biotech is a CRO that supports academics and companies in drug discovery of anticancer products.
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Member of FEDERCHIMICA - ASSOBIOTEC
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Italian Innovative Start-Up
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  • About Us
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