Multidrug Resistance Assay

To determine contribution of ABC transporters to cancer cell chemoresistance of tested compound based on live-cell imaging.
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Features of the assay

• Cells are treated with three selective inhibitors of ABC transporters together with tested compound.
• Number of live/dead cells is measured with our kinetics of cytotoxicity and proliferation assay.
• Relative cell number, relative growth and percentage of growth inhibition calculations.

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Percentage of growth inhibition of SJCRH30 cells treated with drug alone or in combination with ABC transporter inhibitors.

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